Monitoring of occupational exposure to epichlorohydrin by genetic effects and hemoglobin adducts.

@article{Landin1997MonitoringOO,
  title={Monitoring of occupational exposure to epichlorohydrin by genetic effects and hemoglobin adducts.},
  author={H Hindsq Landin and Tamara Grummt and C Laurent and Ad D. Tates},
  journal={Mutation research},
  year={1997},
  volume={381 2},
  pages={217-26}
}
The present work is focused on the determination of in vivo doses and studies of genetic effects in workers exposed to epichlorohydrin (ECH). The studied endpoints were hemoglobin (Hb) adducts, frequencies of hprt mutants, micronuclei in cytochalasin B blocked binucleated lymphocytes, sister chromatid exchanges (SCE) and high frequency cells (HFC). Blood samples were collected from office clerks and ECH exposed factory workers at an industrial plant in Germany. The workers were exposed to 0.11… CONTINUE READING

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