Monitoring of minimal residual disease in acute myeloid leukemia.

  title={Monitoring of minimal residual disease in acute myeloid leukemia.},
  author={Wolfgang Kern and Claudia Haferlach and Torsten Haferlach and Susanne Schnittger},
  volume={112 1},
Two highly sensitive methods, multiparameter flow cytometry (MFC) and real-time quantitative PCR (RQ-PCR), are increasingly used to monitor minimal residual disease (MRD) and to guide risk-adapted management in acute myeloid leukemia (AML). An independent prognostic impact has been demonstrated for MRD levels obtained by both methods. MFC has been found particularly useful for assessment of early clearance of malignant cells and after consolidation therapy. At the latter checkpoint, MRD levels… CONTINUE READING

From This Paper

Topics from this paper.
105 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 105 extracted citations

Similar Papers

Loading similar papers…