Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100.

@article{Homoncik2000MonitoringOA,
  title={Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100.},
  author={Monika Homoncik and Bernd Jilma and Nicole Hergovich and Petra Stohlawetz and Simon Panzer and Wolfgang Speiser},
  journal={Thrombosis and haemostasis},
  year={2000},
  volume={83 2},
  pages={
          316-21
        }
}
BACKGROUND Anti-platelet drug therapy is currently performed without monitoring, because the established method of platelet aggregometry is cumbersome. The recently developed platelet function analyzer PFA-100 measures shear stress dependent, collagen epinephrine (CEPI) and collagen adenosine diphosphate (CADP) induced platelet plug formation. As the PFA-100 provides a valuable tool to detect patients with platelet dysfunction more efficiently and cost-effectively than aggregometry, we… CONTINUE READING
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