Monitoring of antibiotic-induced alterations in the human intestinal microflora and detection of probiotic strains by use of terminal restriction fragment length polymorphism.

@article{Jernberg2005MonitoringOA,
  title={Monitoring of antibiotic-induced alterations in the human intestinal microflora and detection of probiotic strains by use of terminal restriction fragment length polymorphism.},
  author={Cecilia Jernberg and {\AA}sa Sullivan and Charlotta Edlund and Janet K. Jansson},
  journal={Applied and environmental microbiology},
  year={2005},
  volume={71 1},
  pages={501-6}
}
Terminal restriction fragment length polymorphism (T-RFLP) was investigated as a tool for monitoring the human intestinal microflora during antibiotic treatment and during ingestion of a probiotic product. Fecal samples from eight healthy volunteers were taken before, during, and after administration of clindamycin. During treatment, four subjects were given a probiotic, and four subjects were given a placebo. Changes in the microbial intestinal community composition and relative abundance of… CONTINUE READING