Monitoring of HIV viral loads, CD4 cell counts, and clinical assessments versus clinical monitoring alone for antiretroviral therapy in rural district hospitals in Cameroon (Stratall ANRS 12110/ESTHER): a randomised non-inferiority trial.

@article{Laurent2011MonitoringOH,
  title={Monitoring of HIV viral loads, CD4 cell counts, and clinical assessments versus clinical monitoring alone for antiretroviral therapy in rural district hospitals in Cameroon (Stratall ANRS 12110/ESTHER): a randomised non-inferiority trial.},
  author={Christian Laurent and Charles Kouanfack and Gabri{\`e}le Laborde-Balen and Avelin Fobang Aghokeng and Jules Brice Tchatchueng Mbougua and Sylvie Boyer and Maria Patrizia Carrieri and Jean-Marc Mben and Marlise Dontsop and Serge Kaz{\'e} and Nicolas Molinari and Anke Bourgeois and Eitel Mpoudi-Ngol{\'e} and Bruno Spire and Sinata Koulla-Shiro and E. C. Delaporte},
  journal={The Lancet. Infectious diseases},
  year={2011},
  volume={11 11},
  pages={
          825-33
        }
}
BACKGROUND Scaling up of antiretroviral therapy in low-resource countries is done on the basis of decentralised, integrated HIV care in rural facilities; however, laboratory monitoring is generally unavailable. We aimed to assess the effectiveness and safety of clinical monitoring alone (CLIN) in terms of non-inferiority to laboratory and clinical monitoring (LAB). METHODS We did a randomised, open-label, non-inferiority trial in nine rural district hospitals in Cameroon. Eligible… CONTINUE READING

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