Monitoring neutrophils and platelets during casein-induced anaphylaxis in an experimental BALB/c mouse model.

@article{Krishnamurthy2012MonitoringNA,
  title={Monitoring neutrophils and platelets during casein-induced anaphylaxis in an experimental BALB/c mouse model.},
  author={Durga Krishnamurthy and Philipp M. Starkl and Krisztina Katalin Szalai and Franziska Roth-Walter and Susanne C. Diesner and Martina Mittlboeck and Christine Mannhalter and Eva Untersmayr and Erika Jensen-Jarolim},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={2012},
  volume={42 7},
  pages={1119-28}
}
BACKGROUND With respect to the cellular players, mast cells and basophils have been well studied in experimental murine systemic anaphylaxis models, but the role of neutrophils and platelets is not fully understood today. OBJECTIVE We tested the hypothesis that neutrophils and platelets might participate in an antigen-induced anaphylaxis model. METHODS BALB/c mice were sensitized intraperitoneally with alum-adsorbed casein. A period of 2 weeks later, mice were challenged with 100 μg casein… CONTINUE READING
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