Monitoring neuropeptide‐specific proteases: processing of the proopiomelanocortin peptides adrenocorticotropin and α‐melanocyte‐stimulating hormone in the skin

@article{Knig2006MonitoringNP,
  title={Monitoring neuropeptide‐specific proteases: processing of the proopiomelanocortin peptides adrenocorticotropin and α‐melanocyte‐stimulating hormone in the skin},
  author={S. K{\"o}nig and T. Luger and T. Scholzen},
  journal={Experimental Dermatology},
  year={2006},
  volume={15}
}
Abstract:  The neuroendocrine precursor protein proopiomelanocortin (POMC) and its derived neuropeptides are involved in a number of important regulatory processes in the central nervous system as well as in peripheral tissues. Despite its important role in controlling the local activation of melanocortin (MC) receptors, the extracellular proteolytic processing of POMC peptides has received little attention. The mechanisms relevant for controlling the bioavailability of adrenocorticotropin and… Expand
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