Monitoring microevolution of OXA-48-producing Klebsiella pneumoniae ST147 in a hospital setting by SMRT sequencing.

@article{Zautner2017MonitoringMO,
  title={Monitoring microevolution of OXA-48-producing Klebsiella pneumoniae ST147 in a hospital setting by SMRT sequencing.},
  author={Andreas Erich Zautner and Boyke Bunk and Yvonne Pfeifer and Cathrin Spr{\"o}er and Utz Reichard and Helmut Eiffert and Simone Scheithauer and Uwe Gro{\ss} and J{\"o}rg Overmann and Wolfgang Bohne},
  journal={The Journal of antimicrobial chemotherapy},
  year={2017},
  volume={72 10},
  pages={
          2737-2744
        }
}
Objectives Carbapenemase-producing Klebsiella pneumoniae pose an increasing risk for healthcare facilities worldwide. A continuous monitoring of ST distribution and its association with resistance and virulence genes is required for early detection of successful K. pneumoniae lineages. In this study, we used WGS to characterize MDR blaOXA-48-positive K. pneumoniae isolated from inpatients at the University Medical Center Göttingen, Germany, between March 2013 and August 2014. Methods Closed… CONTINUE READING
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