Monitoring membrane potentials in Ehrlich ascites tumor cells by means of a fluorescent dye.

@article{Laris1976MonitoringMP,
  title={Monitoring membrane potentials in Ehrlich ascites tumor cells by means of a fluorescent dye.},
  author={P C Laris and Harrihar A. Pershadsingh and Rose M. Johnstone},
  journal={Biochimica et biophysica acta},
  year={1976},
  volume={436 2},
  pages={475-88}
}
1. The fluorescent intensity of the dye 3,3'-dipropylthiodicarbocyanine iodide was measured in suspensions of Ehrlich ascites tumor cells in an attempt to monitor their membrane potentials under a variety of different ionic and metabolic conditions. 2. In the presence of valinomycin, fluorescent intensity is dependent on log [K+]medium (the fluorescent intensity increased with increasing [K+]medium) where K+ replaced Na+ in the medium. Cellular K+ content also influenced fluorescent intensity… CONTINUE READING

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