Monitoring changes in cyclosporine dosage by trough level testing.

@article{Takasugi1995MonitoringCI,
  title={Monitoring changes in cyclosporine dosage by trough level testing.},
  author={Mikako Takasugi and Julie Takasugi and Lilly M Barba},
  journal={Clinical transplantation},
  year={1995},
  volume={9 2},
  pages={98-105}
}
The concept of a narrow therapeutic window has guided the management of transplant recipients on cyclosporine immunosuppression since its inception more than a decade ago. The need to maintain immunosuppression and avoid toxicity imposed the requirement of monitoring cyclosporine levels within a limited range. The use of circulating trough levels to aid in… CONTINUE READING