Monitoring bone effect of transdermal hormone replacement therapy by ultrasound investigation at the phalanx: a four-year follow-up study.

@article{Mauloni2000MonitoringBE,
  title={Monitoring bone effect of transdermal hormone replacement therapy by ultrasound investigation at the phalanx: a four-year follow-up study.},
  author={Maurizio Mauloni and Lucio Claudio Rovati and Ruggero Cadossi and Francesca de Terlizzi and Ver{\'o}nica Ayala Ventura and Domenico de Aloysio},
  journal={Menopause},
  year={2000},
  volume={7 6},
  pages={402-12}
}
OBJECTIVE A controlled 4-year follow-up study was conducted on a population composed of 112 healthy early postmenopausal women to evaluate the ability of ultrasound technology in detecting the effects of hormone replacement therapy (HRT) on bone. At the end of the study, 47 untreated and 25 treated women had been evaluated. Cyclic sequential estrogen/progestogen therapy, 50 microg/day of transdermal 17beta-estradiol (Rotta Research Laboratorium) plus 5 mg/day of medrogestone (Wyeth-Ayerst) was… CONTINUE READING

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