Monitoring antimalarial drug efficacy: current challenges.

  title={Monitoring antimalarial drug efficacy: current challenges.},
  author={Miriam K Laufer},
  journal={Current infectious disease reports},
  volume={11 1},
Access to effective antimalarial therapy has increased dramatically. As malaria-endemic countries begin to use artemisinin-based combination therapy (ACT) to treat malaria, detecting the emergence and spread of resistance has become more complicated but also more urgent. Clinical efficacy studies may not be sensitive enough to detect the failure of a single component of combination therapy while standardized criteria for in vitro resistance and validated molecular markers are not yet available… CONTINUE READING

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