Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses

@inproceedings{Brinke2017MonitoringTR,
  title={Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses},
  author={Anja ten Brinke and Natalia Maria Marek-Trzonkowska and Mar{\'i}a Jos{\'e} Mansilla and Annelies W. Turksma and Karolina Piekarska and Dorota Iwaszkiewicz-Grześ and Laura Passerini and Grazia Locafaro and Joan Pu{\~n}et-Ortiz and S. Marieke van Ham and Maria P Hernandez-Fuentes and Eva Mar{\'i}a Mart{\'i}nez-C{\'a}ceres and Silvia Gregori},
  booktitle={Front. Immunol.},
  year={2017}
}
Adoptive therapy with regulatory T cells or tolerance-inducing antigen (Ag)-presenting cells is innovative and promising therapeutic approach to control undesired and harmful activation of the immune system, as observed in autoimmune diseases, solid organ and bone marrow transplantation. One of the critical issues to elucidate the mechanisms responsible for success or failure of these therapies and define the specificity of the therapy is the evaluation of the Ag-specific T-cell responses… CONTINUE READING

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