Monitoring Intracellular Oxygen Concentration: Implications for Hypoxia Studies and Real-Time Oxygen Monitoring.

@article{Potter2016MonitoringIO,
  title={Monitoring Intracellular Oxygen Concentration: Implications for Hypoxia Studies and Real-Time Oxygen Monitoring.},
  author={Michelle Potter and Luned Badder and Yvette Hoade and Iain G. Johnston and Karl J Morten},
  journal={Advances in experimental medicine and biology},
  year={2016},
  volume={876},
  pages={257-263}
}
The metabolic properties of cancer cells have been widely accepted as a hallmark of cancer for a number of years and have shown to be of critical importance in tumour development. It is generally accepted that tumour cells exhibit a more glycolytic phenotype than normal cells. In this study, we investigate the bioenergetic phenotype of two widely used cancer cell lines, RD and U87MG, by monitoring intracellular oxygen concentrations using phosphorescent Pt-porphyrin based intracellular probes… CONTINUE READING

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