Monitoring DNA Repair Consequences of ATM Signaling Using Simultaneous Fluorescent Readouts.

Abstract

The repair of deleterious DNA double strand breaks is required to maintain genome integrity. The efficacy in which this occurs relies upon the available machinery and is guided by factors that include cell cycle status, availability of donor template, and the local chromosome structure. Therefore at a single DNA breakpoint there are different outcomes that… (More)
DOI: 10.1007/978-1-4939-6955-5_24

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