Monitoring DNA Contamination in Handled vs. Directly Excavated Ancient Human Skeletal Remains

  title={Monitoring DNA Contamination in Handled vs. Directly Excavated Ancient Human Skeletal Remains},
  author={Elena Pilli and Alessandra Modi and Ciro Serpico and Alessandro Achilli and Hovirag Lancioni and Barbara Lippi and Francesca Bertoldi and Sauro Gelichi and M. Taheri Lari and David Caramelli},
  booktitle={PloS one},
Bones, teeth and hair are often the only physical evidence of human or animal presence at an archaeological site; they are also the most widely used sources of samples for ancient DNA (aDNA) analysis. Unfortunately, the DNA extracted from ancient samples, already scarce and highly degraded, is widely susceptible to exogenous contaminations that can affect the reliability of aDNA studies. We evaluated the molecular effects of sample handling on five human skeletons freshly excavated from a… CONTINUE READING
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