Mometasone furoate: an effective anti‐inflammatory with a well‐defined safety and tolerability profile in the treatment of asthma

@article{Bousquet2009MometasoneFA,
  title={Mometasone furoate: an effective anti‐inflammatory with a well‐defined safety and tolerability profile in the treatment of asthma},
  author={Jean Bousquet},
  journal={International Journal of Clinical Practice},
  year={2009},
  volume={63}
}
  • J. Bousquet
  • Published 1 May 2009
  • Medicine
  • International Journal of Clinical Practice
Inhaled corticosteroids (ICS) are recommended as a controller medication in the most recent Global Initiative for Asthma and the National Heart, Lung and Blood Institute guidelines. Mometasone furoate (MF) is an effective, well‐tolerated inhaled steroid and is indicated for the maintenance treatment of adult and adolescent patients (≥ 12 years) with persistent asthma. MF is approved for once or bid maintenance treatment of asthma (in patients previously receiving ICS or bronchodilators). Low… 
Mometasone furoate: an inhaled glucocorticoid for the management of asthma in adults and children
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Introduction: Asthma is one of the most frequent chronic diseases worldwide. For decades, asthma has been treated with bronchodilators and inhaled corticosteroids (ICS). However, adverse effects of
Using Lower Doses of Topical Mometasone Furoate in the Treatment of Atopic Dermatitis by Applying Hyaluronic Acid as a Skin Penetration Enhancer
The objective of the present study was to investigate the possibility to add hyaluronic acid (HA) as skin penetration enhancers to mometasone furoate (MF) to enhance its skin absorption, and so
Local delivery of mometasone furoate from an eluting endotracheal tube
Investigation of Appropriate Inhalation Technique for Mometasone Furoate Dry Powder Inhaler.
TLDR
PIFR but not Tmax PIFR has an effect on lung deposition after inhalation with an MF-DPI, and FPF for the claimed dose was significantly lower than that at 60 L/min, which was dependent on PifR.
Topical Administration of Mometasone Furoate - A Combined Impedance Spectroscopy and In Vitro Drug Diffusion Study
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To conclude, cream B appears to be the safer alternative as it does not seem to perturb the skin and imposes less systemic burden without sacrificing clinical efficacy.
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TLDR
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TLDR
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Reduction in Oral Corticosteroid Use with Mometasone Furoate Dry Powder Inhaler Improves Health-Related Quality of Life in Patients with Severe Persistent Asthma
TLDR
Symptomatic improvement and reduction in OCS use with MF DPI were accompanied by significant improvement in HRQL in patients with severe persistent asthma, and improvements were maintained during the 3-month period of the OLE in which HRQL was evaluated.
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