Molecules with versatile biological activities bearing antipyrinyl nucleus as pharmacophore.

@article{Sahoo2019MoleculesWV,
  title={Molecules with versatile biological activities bearing antipyrinyl nucleus as pharmacophore.},
  author={J. Sahoo and C. R. Sahoo and Priyambada Kshiroda Nandini Sarangi and S. K. Prusty and R. Padhy and Sudhir K. Paidesetty},
  journal={European journal of medicinal chemistry},
  year={2019},
  pages={
          111911
        }
}
Antipyrine (1,2-dihydro-1,5-dimethyl-2-phenylpyrazole-3-one) in a structural frame consists of a five membered lactam pyrazolone heterocyclic ring as a pharmacophore moiety. It is evident from literature that the molecules having nitrogen bearing heterocyclic nuclei clearly exhibit several biological actions. Commercially available pyrazolone derivatives as drugs, analgin and metamizol are an established chemical class of analgesics. Recent trends of synthetic routes and several biological… Expand

References

SHOWING 1-10 OF 71 REFERENCES
Antibacterial and cytotoxic activities of Schiff base analogues of 4-aminoantipyrine
  • 16
New celecoxib derivatives as anti-inflammatory agents.
  • 131
Norharmane as a potential chemical entity for development of anticancer drugs.
  • 7
Synthesis and antiviral activity of 2-amino-3-ethoxycarbonylpyrazine derivatives
  • 13
...
1
2
3
4
5
...