Molecules involved in reactive sprouting in the hippocampus.

  title={Molecules involved in reactive sprouting in the hippocampus.},
  author={Nicolai Savaskan and Robert Nitsch},
  journal={Reviews in the neurosciences},
  volume={12 3},
Denervation of the hippocampus triggers reactive responses in neurons and glial cells in their affected strata in a temporally ordered fashion. Many of these responses have been studied extensively, focusing on the one hand on glial initiation and clearing responses during the degeneration phase and, on the other, on transneuronal reorganization and the newly adjusted physiological balance. We used the entorhinal cortex lesion (ECL) as a model system to study the cues that underlie the layer… CONTINUE READING
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