Molecularly targeted therapies for recurrent glioblastoma: current and future targets.

@article{Lau2014MolecularlyTT,
  title={Molecularly targeted therapies for recurrent glioblastoma: current and future targets.},
  author={Darryl Lau and Stephen T Magill and Manish K Aghi},
  journal={Neurosurgical focus},
  year={2014},
  volume={37 6},
  pages={E15}
}
OBJECT Glioblastoma is the most aggressive and diffusely infiltrative primary brain tumor. Recurrence is expected and is extremely difficult to treat. Over the past decade, the accumulation of knowledge regarding the molecular and genetic profile of glioblastoma has led to numerous molecularly targeted therapies. This article aims to review the literature and highlight the mechanisms and efficacies of molecularly targeted therapies for recurrent glioblastoma. METHODS A systematic search was… CONTINUE READING
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