Molecularly engineered p(HEMA)-based hydrogels for implant biochip biocompatibility.

@article{Abraham2005MolecularlyEP,
  title={Molecularly engineered p(HEMA)-based hydrogels for implant biochip biocompatibility.},
  author={S. Daniel Abraham and Sean Brahim and Kazuhiko Ishihara and Anthony Guiseppi-Elie},
  journal={Biomaterials},
  year={2005},
  volume={26 23},
  pages={4767-78}
}
The strategy of phospholipid-based biomimicry has been used to molecularly engineer poly(2-hydroxyethyl methacrylate) [p(HEMA)]-based hydrogels for improved in vitro and potential in vivo biocompatibility. Two methacrylate-based monomers, poly(ethylene glycol) (200) monomethacrylate (PEGMA) and 2-methacryloyloxyethyl phosphorylcholine (MPC), were incorporated at varying mole fractions of 0.0-0.5 mol% PEGMA and 0-10 mol% MPC respectively, into 3 mol% tetraethyleneglycol diacrylate (TEGDA) cross… CONTINUE READING