Molecular virology: Was the 1918 flu avian in origin?

  title={Molecular virology: Was the 1918 flu avian in origin?},
  author={J. Antonovics and M. Hood and C. Baker},
Arising from: J. K. Taubenberger et al. 437, 889–893 (2005); see also communication from Gibbs and Gibbs; Taubenberger et al. replyTaubenberger et al. claim that the 1918 influenza virus was derived from an avian source and adapted to humans shortly before the pandemic. However, we do not believe that this conclusion, which has been widely disseminated in the popular press and in scientific journals, is supported by their phylogenetic evidence. 
Molecular virology: Was the 1918 pandemic caused by a bird flu? Was the 1918 flu avian in origin? (Reply)
We have proposed that the virus responsible for the 1918 human influenza pandemic was avian-like, which to us is a reasonable interpretation of all the available data from phylogenetic, sequence,Expand
The matrix segment of the “Spanish flu” virus originated from intragenic recombination between avian and human influenza A viruses
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Phylogenetic evidence for a mild H1 pandemic in the early 1900s
  • S. Riley
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2014
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The Evolution and Emergence of RNA Viruses
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Phylogenetic analysis of pandemic influenza A/H1N1 virus
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Homologous recombination evidence in human and swine influenza A viruses.
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Emerging Disease and the Evolution of Virulence: The Case of the 1918–1919 Influenza Pandemic
“Why do parasites harm their host?” is a recurrent question in evolutionary biology and ecology, and has several implications for the biomedical sciences, particularly public health and epidemiology.Expand
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The origins of pandemic influenza--lessons from the 1918 virus.
  • R. Belshe
  • Medicine
  • The New England journal of medicine
  • 2005
What the 1918 virus teaches us about avian H5N1 influenza is described by Dr. Robert Belshe. Expand
1918 Flu and Responsible Science
  • P. Sharp
  • Political Science, Medicine
  • Science
  • 2005
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Characterization of the 1918 influenza virus polymerase genes
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Novel Origin of the 1918 Pandemic Influenza Virus Nucleoprotein Gene
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Evidence of an absence: the genetic origins of the 1918 pandemic influenza virus
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There are remarkable similarities between the polymerase genes of the influenza virus that caused the 1918 Spanish influenza pandemic and those of avian influenza viruses. Expand
MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment
An overview of the statistical methods, computational tools, and visual exploration modules for data input and the results obtainable in MEGA is provided. Expand