Molecular understanding of a potential functional link between antimicrobial and amyloid peptides.

@article{Zhang2014MolecularUO,
  title={Molecular understanding of a potential functional link between antimicrobial and amyloid peptides.},
  author={Mingzhen Zhang and Jun Zhao and Jie Zheng},
  journal={Soft matter},
  year={2014},
  volume={10 38},
  pages={7425-51}
}
Antimicrobial and amyloid peptides do not share common sequences, typical secondary structures, or normal biological activity but both the classes of peptides exhibit membrane-disruption ability to induce cell toxicity. Different membrane-disruption mechanisms have been proposed for antimicrobial and amyloid peptides, individually, some of which are not exclusive to either peptide type, implying that certain common principles may govern the folding and functions of different cytolytic peptides… CONTINUE READING