Molecular tolerance of voltage-gated calcium channels is evident after short exposures to alcohol in vasopressin-releasing nerve terminals.

Abstract

BACKGROUND Voltage-gated calcium channels (VGCCs) in rat neurohypophysial terminals exhibit molecular tolerance to alcohol, including desensitization to the drug and increased current density, after 3 weeks of alcohol drinking. Moreover, after this time, terminals from drinking rats exhibit diminished alcohol inhibition of vasopressin (AVP) release… (More)
DOI: 10.1111/acer.12057

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Cite this paper

@article{Pietrzykowski2013MolecularTO, title={Molecular tolerance of voltage-gated calcium channels is evident after short exposures to alcohol in vasopressin-releasing nerve terminals.}, author={Andrzej Zbigniew Pietrzykowski and Sonia I Ortiz-Miranda and Thomas Kris Knott and Edward E. Custer and Sylvie I. Puig and Jos{\'e} Ribeiro Lemos and Steven N. Treistman}, journal={Alcoholism, clinical and experimental research}, year={2013}, volume={37 6}, pages={933-40} }