Molecular therapy in support to radiotherapy.

Abstract

Approximately half of all cancer patients are treated with radiation therapy. However, some tumor cells can escape the lethal effects of irradiation by hypoxia, deregulation of the cell cycle or apoptosis or by increasing their ability to repair the DNA damage induced, resulting in recurrence of disease. In order to overcome these resistance mechanisms… (More)
DOI: 10.1016/j.mrrev.2010.01.001

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