Molecular studies of liver aldolase B in hereditary fructose intolerance using blotting and immunological techniques.

@article{Gregori1982MolecularSO,
  title={Molecular studies of liver aldolase B in hereditary fructose intolerance using blotting and immunological techniques.},
  author={Claudine Gregori and Fanny Schapira and Axel Kahn and Marc Delpech and Jean Claude Dreyfus},
  journal={Annals of human genetics},
  year={1982},
  volume={46 Pt 4},
  pages={281-92}
}
Hereditary fructose intolerance is due to a deficiency of liver aldolase (aldolase B). Little is known about its molecular mechanisms. We have tried to demonstrate the presence of the molecule and have explored the possibility of genetic heterogeneity. Liver samples from fifteen cases of hereditary fructose intolerance due to aldolase B deficiency were studied by various electrophoretic techniques. After electrophoresis on polyacrylamide gels, proteins were electrophoretically transferred on to… CONTINUE READING