Molecular structure of phospholipase D and regulatory mechanisms of its activity in plant and animal cells

@article{Kolesnikov2012MolecularSO,
  title={Molecular structure of phospholipase D and regulatory mechanisms of its activity in plant and animal cells},
  author={Yaroslav S. Kolesnikov and Kateryna Nokhrina and Sergii Kretynin and Igor D. Volotovski and Jan Martinec and Georgy A. Romanov and V. S. Kravets},
  journal={Biochemistry (Moscow)},
  year={2012},
  volume={77},
  pages={1-14}
}
Phospholipase D (PLD) catalyzes hydrolysis of phospholipids with production of phosphatidic acid, which often acts as secondary messenger of transduction of intracellular signals. This review summarizes data of leading laboratories on specific features of organization and regulation of PLD activity in plant and animal cells. The main structural domains of PLD (C2, PX, PH), the active site, and other functionally important parts of the enzyme are discussed. Regulatory mechanisms of PLD activity… 

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References

SHOWING 1-10 OF 257 REFERENCES

Clin Cancer Res

  • 2010

New Phytol

This study highlights the need to understand more fully the phytochemical properties of Cannabis sativa, which has the potential to act as a ‘spatially aggregating agent’ to form cannabis plants.

FEBS Lett

Arabidopsis Phospholipase Dα1 Interacts with the Heterotrimeric G-protein α-Subunit through a Motif Analogous to the DRY Motif in G-protein-coupled Receptors*

These results have demonstrated the direct binding between Gα and PLDα1, identified the DRY motif on PLDalpha1 as the site for the interaction, and indicated that the interaction modulates reciprocally the activities of PLD α1 and Gα.
...