Molecular structure and antioxidant specificity of purpurogallin in three types of human cardiovascular cells.

@article{Wu1996MolecularSA,
  title={Molecular structure and antioxidant specificity of purpurogallin in three types of human cardiovascular cells.},
  author={T W Wu and L. H. Zeng and Jinrong Wu and Kwok Pui Fung and Richard D. Weisel and Andrew Hempel and Norman Camerman},
  journal={Biochemical pharmacology},
  year={1996},
  volume={52 7},
  pages={
          1073-80
        }
}
Purpurogallin (PPG) in an active cytoprotector found in certain oak barks. We have shown that PPG prolongs the survival of cultured cardiocytes from rats and rabbits against different oxidants better than do antioxidants such as Trolox (a hydrophilic analogue of vitamin E) in a morphometric assay system. First, we verified by X-ray crystallography that PPG is a bicyclic molecule comprising a phenolic ring fused with a seven-membered ring in a highly planar conformation. In analogues of PPG… CONTINUE READING

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Metabolism of pyrogallol to purpurogallin by human erythrocytic hemoglobin.

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  • 2004
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