Molecular signatures of pancreatic cancer.

@article{Hong2011MolecularSO,
  title={Molecular signatures of pancreatic cancer.},
  author={Seung-Mo Hong and Jason J. Y. Park and Ralph H. Hruban and Michael G. Goggins},
  journal={Archives of pathology & laboratory medicine},
  year={2011},
  volume={135 6},
  pages={
          716-27
        }
}
CONTEXT The introduction of genome- and epigenome-wide screening techniques has dramatically improved our understanding of the molecular mechanisms underlying the development of pancreatic cancer. There are now 3 recognized histologic precursors of pancreatic cancer: pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasm, and mucinous cystic neoplasm. Each of these precursor lesions is associated with specific molecular alterations. OBJECTIVE To understand the molecular… CONTINUE READING

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