Molecular signatures of maturing dendritic cells: implications for testing the quality of dendritic cell therapies

@inproceedings{Jin2009MolecularSO,
  title={Molecular signatures of maturing dendritic cells: implications for testing the quality of dendritic cell therapies},
  author={Ping Jin and Tae Hee Han and Jiaqiang Ren and Stefanie Saunders and Ena Wang and Francesco M. Marincola and David F Stroncek},
  booktitle={Journal of Translational Medicine},
  year={2009}
}
Dendritic cells (DCs) are often produced by granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4) stimulation of monocytes. To improve the effectiveness of DC adoptive immune cancer therapy, many different agents have been used to mature DCs. We analyzed the kinetics of DC maturation by lipopolysaccharide (LPS) and interferon… CONTINUE READING