Molecular responses of human dermal fibroblasts to dual cues: contact guidance and mechanical load.

@article{Mudera2000MolecularRO,
  title={Molecular responses of human dermal fibroblasts to dual cues: contact guidance and mechanical load.},
  author={Vivek C. Mudera and Robert D Pleass and Mark Eastwood and Roy W. Tarnuzzer and G{\"u}nter Schultz and Peng T. Khaw and D. A. Mcgrouther and RobertA. Brown},
  journal={Cell motility and the cytoskeleton},
  year={2000},
  volume={45 1},
  pages={
          1-9
        }
}
Fibroblast contraction in wound healing involves the interaction of several cell types, cytokines, and extracellular matrix molecules. We have previously developed fibroblast alignment models using precise uniaxial mechanical loads in 3D culture and using contact guidance on fibronectin strands. Our aim here was to use contact guidance to place fibroblasts in their potentially most sensitive configuration, i.e., perpendicular to the axis of loading, to present cells with conflicting guidance… CONTINUE READING
BETA

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 65 CITATIONS, ESTIMATED 59% COVERAGE

FILTER CITATIONS BY YEAR

2001
2019

CITATION STATISTICS

  • 5 Highly Influenced Citations

Similar Papers

Loading similar papers…