Molecular requirements for assembly and function of a minimized human integrin alphaIIbbeta3.

@article{McKay1996MolecularRF,
  title={Molecular requirements for assembly and function of a minimized human integrin alphaIIbbeta3.},
  author={Brian S. McKay and Douglas S. Annis and Shinya Honda and Duncan Christie and Thomas J. Kunicki},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 48},
  pages={30544-7}
}
Integrin subunit compatibility within and between species plays a major role in heterodimer assembly and ligand specificity. As an example, human alphaIIb pairs only with human beta3 and does not assemble a heterodimer with beta3 from other species. We use interspecies subunit chimeras to identify molecular requirements for subunit compatibility and show… CONTINUE READING