Molecular recognition in the human immunodeficiency virus capsid and antiviral design.

@article{Bocanegra2012MolecularRI,
  title={Molecular recognition in the human immunodeficiency virus capsid and antiviral design.},
  author={Rebeca Bocanegra and Alicia Rodr{\'i}guez-Huete and Miguel {\'A}ngel Fuertes and Marta del {\'A}lamo and Mauricio G Mateu},
  journal={Virus research},
  year={2012},
  volume={169 2},
  pages={388-410}
}
Many compounds able to interfere with HIV-1 infection have been identified; some 25 of them have been approved for clinical use. Current anti-HIV-1 therapy involves the use of drug cocktails, which reduces the probability of virus escape. However, many issues remain, including drug toxicity and the emergence of drug-resistant mutant viruses, even in treated… CONTINUE READING