Molecular recognition by the KIX domain and its role in gene regulation

@inproceedings{Thakur2014MolecularRB,
  title={Molecular recognition by the KIX domain and its role in gene regulation},
  author={Jitendra Kumar Thakur and Archana Yadav and Gitanjali Yadav},
  booktitle={Nucleic acids research},
  year={2014}
}
The kinase-inducible domain interacting (KIX) domain is a highly conserved independently folding three-helix bundle that serves as a docking site for transcription factors, whereupon promoter activation and target specificity are achieved during gene regulation. This docking event is a harbinger of an intricate multi-protein assembly at the transcriptional apparatus and is regulated in a highly precise manner in view of the critical role it plays in multiple cellular processes. KIX domains have… CONTINUE READING

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Prepaying the entropic cost for allosteric regulation in KIX.

Proceedings of the National Academy of Sciences of the United States of America • 2014

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The allosteric communication pathways in KIX domain of CBP.

Proceedings of the National Academy of Sciences of the United States of America • 2013

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