Molecular properties of voltage-gated K+ channels.

  title={Molecular properties of voltage-gated K+ channels.},
  author={J Oliver Dolly and David N. Parcej},
  journal={Journal of bioenergetics and biomembranes},
  volume={28 3},
Subfamilies of voltage-activated K+ channels (Kv1-4) contribute to controlling neuron excitability and the underlying functional parameters. Genes encoding the multiple alpha subunits from each of these protein groups have been cloned, expressed and the resultant distinct K+ currents characterized. The predicted amino acid sequences showed that each alpha subunit contains six putative membrane-spanning alpha-helical segments (S1-6), with one (S4) being deemed responsible for the channels… CONTINUE READING

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