Molecular profiling of the human testis reveals stringent pathway-specific regulation of RNA expression following gonadotropin suppression and progestogen treatment.

Abstract

Gonadotropin withdrawal induces changes in gene expression in all 3 major cell types of the testis. Knowledge of the genes affected, in both the presence and absence of additional progestogen, will give insight into the regulation of human testicular function and aid development of novel contraceptive methods. We have undertaken a whole-genome analysis of… (More)

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@article{Bayne2008MolecularPO, title={Molecular profiling of the human testis reveals stringent pathway-specific regulation of RNA expression following gonadotropin suppression and progestogen treatment.}, author={Rosemary A. L. Bayne and Thorsten Forster and Stewart T. G. Burgess and Marie H. Craigon and Melanie J Walton and David Baird and Peter Ghazal and Richard A. Anderson}, journal={Journal of andrology}, year={2008}, volume={29 4}, pages={389-403} }