Molecular profiling of non-small cell lung cancer and correlation with disease-free survival.

@article{Wigle2002MolecularPO,
  title={Molecular profiling of non-small cell lung cancer and correlation with disease-free survival.},
  author={Dennis A. Wigle and Igor Jurisica and Niki Radulovich and Melania Pintilie and Janet Rossant and Ni Liu and Chao Lu and James R Woodgett and Isolde Seiden and Michael D Johnston and Shaf H Keshavjee and Gail Elizabeth Darling and Timothy R Winton and Bobby-Joe Breitkreutz and Paul Jorgenson and Mike Tyers and Frances A. Shepherd and Ming Sound Tsao},
  journal={Cancer research},
  year={2002},
  volume={62 11},
  pages={3005-8}
}
Recent studies have suggested that information from gene expression profiles could be used to develop molecular classifications of cancer. We hypothesized that expression levels of specific genes in operative specimens could be correlated to recurrence risk in non-small cell lung cancer (NSCLC). We performed expression profiling using 19.2 K cDNA microarrays on tumor specimens from a total of 39 NSCLC patients with known clinical follow-up information. Statistical analysis and clustering… CONTINUE READING

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: application of a three - tiered approach

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