Molecular profiling of head and neck squamous cell carcinoma

@inproceedings{Feldman2016MolecularPO,
  title={Molecular profiling of head and neck squamous cell carcinoma},
  author={Rebecca A Feldman and Zoran Gatalica and Joseph A Knezetic and Sandeep Steven Reddy and Cherie‐Ann Nathan and Nader Javadi and Theodoros Teknos},
  booktitle={Head & neck},
  year={2016}
}
BACKGROUND Head and neck squamous cell carcinoma (HNSCC) exhibits high rates of recurrence, and with few approved targeted agents, novel treatments are needed. We analyzed a molecular profiling database for the distribution of biomarkers predictive of chemotherapies and targeted agents. METHODS Seven hundred thirty-five patients with advanced HNSCC (88 with known human papillomavirus [HPV] status), were profiled using multiple platforms (gene sequencing, gene copy number, and protein… CONTINUE READING

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