Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network.

@article{Weller2009MolecularPO,
  title={Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network.},
  author={Michael Weller and Joerg Felsberg and Christian Hartmann and Hilmar Berger and Joachim Peter Steinbach and Johannes Schramm and Manfred Westphal and Gabriele Schackert and Matthias Simon and Joerg Christian Tonn and Oliver Heese and Dietmar Krex and Guido Nikkhah and Torsten Pietsch and Otmar Dieter Wiestler and Guido Reifenberger and Andreas von Deimling and Markus L{\"o}ffler},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2009},
  volume={27 34},
  pages={5743-50}
}
PURPOSE The prognostic value of genetic alterations characteristic of glioblastoma in patients treated according to present standards of care is unclear. PATIENTS AND METHODS Three hundred one patients with glioblastoma were prospectively recruited between October 2004 and December 2006 at the clinical centers of the German Glioma Network. Two hundred fifty-eight patients had radiotherapy, 199 patients had temozolomide, 189 had both, and seven had another chemotherapy as the initial treatment… CONTINUE READING
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