Molecular prediction of response to 5-fluorouracil and interferon-alpha combination chemotherapy in advanced hepatocellular carcinoma.

@article{Kurokawa2004MolecularPO,
  title={Molecular prediction of response to 5-fluorouracil and interferon-alpha combination chemotherapy in advanced hepatocellular carcinoma.},
  author={Yukinori Kurokawa and Ryo Matoba and Hiroaki Nagano and Masato Sakon and Ichiro Takemasa and Shoji Nakamori and Keizo Dono and Koji Umeshita and Noriko Ueno and Shin Ishii and Kikuya Kato and Morito Monden},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2004},
  volume={10 18 Pt 1},
  pages={
          6029-38
        }
}
PURPOSE The prognosis of hepatocellular carcinoma (HCC) is very poor, particularly in patients with tumors that have invaded the major branches of the portal vein. Combination chemotherapy with intra-arterial 5-fluorouracil and subcutaneous interferon-alpha has shown promising results for such advanced HCC, but it is important to develop the ability to accurately predict chemotherapeutic responses. EXPERIMENTAL DESIGN We analyzed the expression of 3,080 genes using a polymerase chain reaction… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 26 CITATIONS

Hepatocellular carcinoma: molecular pathways and new therapeutic targets.

  • Seminars in liver disease
  • 2005
VIEW 14 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 45 REFERENCES

PCR-array gene expression profiling of hepatocellular carcinoma.

  • Journal of experimental & clinical cancer research : CR
  • 2004

Similar Papers

Loading similar papers…