Molecular physiology of the tensin brotherhood of integrin adaptor proteins.

  title={Molecular physiology of the tensin brotherhood of integrin adaptor proteins.},
  author={D. T. Haynie},
  volume={82 7},
Numerous proteins have been identified as constituents of the adhesome, the totality of molecular components in the supramolecular assemblies known as focal adhesions, fibrillar adhesions and other kinds of adhesive contact. The transmembrane receptor proteins called integrins are pivotal adhesome members, providing a physical link between the extracellular matrix (ECM) and the actin cytoskeleton. Tensins are ever more widely investigated intracellular adhesome constituents. Involved in cell… CONTINUE READING
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