Molecular physiology of the dynamic regulation of carbon catabolite repression in Escherichia coli.

@article{Borirak2014MolecularPO,
  title={Molecular physiology of the dynamic regulation of carbon catabolite repression in Escherichia coli.},
  author={Orawan Borirak and Martijn Bekker and Klaas J. Hellingwerf},
  journal={Microbiology},
  year={2014},
  volume={160 Pt 6},
  pages={1214-23}
}
We report on the use of the chemostat as an optimal device to create time-invariant conditions that allow accurate sampling for various omics assays in Escherichia coli, in combination with recording of the dynamics of the physiological transition in the organism under study that accompany the initiation of glucose repression. E. coli cells respond to the… CONTINUE READING