Molecular phenotypes of notochordal cells purified from immature nucleus pulposus

@article{Chen2006MolecularPO,
  title={Molecular phenotypes of notochordal cells purified from immature nucleus pulposus},
  author={Jun Chen and Wei Yan and Lori A. Setton},
  journal={European Spine Journal},
  year={2006},
  volume={15},
  pages={303-311}
}
The immature nucleus pulposus (NP) is populated by cells of notochordal-origin that are larger and contain an extensive cytoskeletal network and numerous vacuoles. The disappearance of these cells with age is believed important in regulating metabolic shifts that may contribute to age-related disc degeneration. The precise biological function of these notochordal cells in the immature NP remains unclear, however, because of challenges in studying the mixed cell population in the NP. In this… CONTINUE READING
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Biosynthesis of notochordal cells isolated via a novel fluorescence - based sorting protocol

  • J Chen, W Yan, LA Setton
  • 2004

Biosynthesis of notochordal cells isolated via a novel fluorescence-based sorting protocol. 31st annual meeting of The International Society for Study of the Lumbar Spine

  • J Chen, W Yan, LA Setton
  • 2004
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