Molecular pharmacology of somatostatin receptors

@article{Hoyer1994MolecularPO,
  title={Molecular pharmacology of somatostatin receptors},
  author={Daniel Hoyer and Hermann Luebbert and Christian Bruns},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1994},
  volume={350},
  pages={441-453}
}
The neuropeptide somatostatin (SRIF) is widely expressed in the brain and in the periphery in two main forms, SRIF-14 and SRIF-28. Similarly, the presence of SRIF receptors throughout the whole body has been reported. SRIF produces a variety of effects including modulation of hormone release (e.g. GH, glucagon, insulin), of neurotransmitter release (e.g. acetylcholine, dopamine, 5-HT), and its own release is modulated by many neurotransmitters. SRIF affects cognitive and behavioural processes… CONTINUE READING

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