Molecular pharmacology of 5-HT1D recognition sites: Radioligand binding studies in human, pig and calf brain membranes

@article{Waeber2004MolecularPO,
  title={Molecular pharmacology of 5-HT1D recognition sites: Radioligand binding studies in human, pig and calf brain membranes},
  author={C. Waeber and P. Schoeffter and J. Palacios and D. Hoyer},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2004},
  volume={337},
  pages={595-601}
}
Summary1)The binding characteristics of [3H]5-HT (5-hydroxytryptamine, serotonin) were investigated in membrane preparations of several regions from calf, pig and human brain in the presence of 100 nmol/l 8-OH-DPAT (8-hydroxy-2[di-n-dipropylamino]tetralin) and 100 nmol/l mesulergine in order to mask 5-HT1A and 5-HT1C sites.2)[3H]5-HT bound rapidly, reversibly and stereo-selectively to a population of high affinity recognition sites in membranes from pig caudate, calf caudate and human cortex… Expand
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References

SHOWING 1-10 OF 41 REFERENCES
Characterization of a novel 3H-5-hydroxytryptamine binding site subtype in bovine brain membranes
  • R. E. Heuring, S. Peroutka
  • Biology, Medicine
  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1987
Visualization of a novel serotonin recognition site (5-HT1D) in the human brain by autoradiography
5-HT1A-receptors mediate stimulation of adenylate cyclase in rat hippocampus
...
1
2
3
4
5
...