Molecular pharmacological basis of the YiSui ShenXu Granule in beta-thalassemia therapy.

@article{Zhang2008MolecularPB,
  title={Molecular pharmacological basis of the YiSui ShenXu Granule in beta-thalassemia therapy.},
  author={Chong Zhang and Zhi-kui Wu},
  journal={Journal of ethnopharmacology},
  year={2008},
  volume={120 3},
  pages={
          437-41
        }
}
OBJECTIVES To study the molecular pharmacological basis of the YiSui ShenXu Granule, a complex prescription of the Chinese traditional medicine used to treat beta-thalassemia. METHODS Real-time quantitative PCR method had been applied to analyze the genes expression: gamma-globin, Ckit, EpoR, Spi, FKLF, GATA1 and GATA2 in K562 cell treated and untreated with this complex prescription and its each single herbal medicine. RESULTS The results showed that this complex prescription increased the… CONTINUE READING