Molecular patterning along the sea urchin animal-vegetal axis.

@article{Brandhorst2002MolecularPA,
  title={Molecular patterning along the sea urchin animal-vegetal axis.},
  author={Bruce Peter Brandhorst and William H. Klein},
  journal={International review of cytology},
  year={2002},
  volume={213},
  pages={183-232}
}
The molecular regulatory mechanisms underlying primary axis formation during sea urchin development have recently been identified. Two opposing maternally inherited systems, one animalizing and one vegetalizing, set up the animal-vegetal (A-V) axis. The vegetal system relies in part on the Wnt-beta-catenin-Tcf/Lef signaling pathway and the animal system is based on a cohort of animalizing transcription factors that includes members of the Ets and Sox classes. The two systems autonomously define… CONTINUE READING

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