Molecular pathways in virus-induced cytokine production.

@article{Mogensen2001MolecularPI,
  title={Molecular pathways in virus-induced cytokine production.},
  author={Trine Hyrup Mogensen and S\oren R Paludan},
  journal={Microbiology and molecular biology reviews : MMBR},
  year={2001},
  volume={65 1},
  pages={
          131-50
        }
}
Virus infections induce a proinflammatory response including expression of cytokines and chemokines. The subsequent leukocyte recruitment and antiviral effector functions contribute to the first line of defense against viruses. The molecular virus-cell interactions initiating these events have been studied intensively, and it appears that viral surface glycoproteins, double-stranded RNA, and intracellular viral proteins all have the capacity to activate signal transduction pathways leading to… CONTINUE READING
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