Molecular organization of the vestigial region in Drosophila melanogaster.

The vestigial (vg) locus of Drosophila melanogaster is involved in wing margin development. In the absence of a vg+ gene, extensive cell death occurs in third instar imaginal discs which results in a complete loss of adult wing margin structures. P-element tagging was used to obtain a molecular clone of the vg locus, which led to the molecular… (More)