Molecular organization of the class I genes of human major histocompatibility complex.

@article{Srivastava1985MolecularOO,
  title={Molecular organization of the class I genes of human major histocompatibility complex.},
  author={Rakesh P. Srivastava and Barry W. Duceman and P. A. Biro and Ashwam K. Sood and Sherman Morton Weissman},
  journal={Immunological reviews},
  year={1985},
  volume={84},
  pages={93-121}
}
In this brief review, our main emphasis has been on the analysis of the sequence diversity among various class I genes and their functional implications. The availability of complete nucleotide sequences of 7 different genes representing different loci allowed us to derive a consensus sequence. One mouse MHC Class I gene was included in these comparisons as a representative of H2 genes Evolutionary patterns can be seen on the basis of divergence of various genes from the derived consensus… CONTINUE READING
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